We do both basic and applied research in Microbiology and have various national and international projects. Corpogen has three research groups:

 

 

  • Molecular Biotechnology
  • Molecular Genetics
  • Bioinformatics
 

See recent publications

Research

Projects

Resistance and adaptation

  • Acquisition of resistance and persistance in Klebsiella pneumoniae clincal isolates

  • Microbial communities asscociated with endotracheal tubes in ICU patients

  • ARGs in the Bogotá River

Microbial diversity

  • Identification and conservation of microorganisms isolated from soil and water from extreme habitats in Colombia

  • Lichen microbial communities

  • Microorganismos in the bus transport system

Mycobacterium tuberculosis Biomarkers

  • Molecular diagnostics 

  • Transcriptomics

Metabolites and microbial enzymes

  • Study of biosynthetic gene clusters in Streptomyces strains

  • Microbial enzymes to promote industrial mushroom cultivation

  • Development of a transposon tool for enhanced gene expression from metagenomic libraries

Bioinformatics

  • Metabolic potential present in genomes and metagenomes

  • Identification of enzymes in metagenomes

Recent Publications

 
  • The effect of aminoglycosides on horizontal gene transfer in Klebsiella pneumoniae. Acosta IA et al. Rev. Acad. Colomb. Cienc. Ex. Fis. Nat. 2020. 44(170):105-120.

  • The Microbiomes of Seven Lichen Genera Reveal Host Specificity, a Reduced Core Community and Potential as Source of Antimicrobials. Sierrra MA et al. Front. Microbiol. 2020. 11:398. doi: 10.3389/fmicb.2020.00398

  • Bogotá River anthropogenic contamination alters microbial communities and promotes spread of antibiotic resistance genes. Posada-Perlaza CE et al. Sci Rep. 2019 Aug 13;9(1):11764. doi: 10.1038/s41598-019-48200-6. PMID:31409850

  • Global phylogeography and ancient evolution of the widespread human gut virus crAssphage. Edwards RA et al. Nat Microbiol. 2019 Oct;4(10):1727-1736. doi: 10.1038/s41564-019-0494-6. PMID: 31285584.

  • Recovery and functional validation of hidden soil enzymes in metagenomic libraries. Calderon D et al. MicrobiologyOpen. 2019 Apr;8(4):e00572. doi: 10.1002/mbo3.572. Epub 2019 Mar 9. PMID: 30851083

 

  • Hypoxia Is Not a Main Stress When Mycobacterium tuberculosis Is in a Dormancy-Like Long-Chain Fatty Acid Environment. Del Portillo P et al. Front Cell Infect Microbiol. 2019 Jan 9;8:449. doi: 10.3389/fcimb.2018.00449. eCollection 2018. PMID:30687646

 

 

 

Contact:

Corporación Corpogen

Carrera 4 # 20-41, Bogotá, DC

Tel: +57-312-4064841

Email: corpogen@corpogen.org